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ST6Gal1: Oncogenic signaling pathways and targets

The Golgi-sialyltransferase ST6Gal1 (βgalactosidase α2,6 sialyltransferase 1), adds the negatively charged sugar, sialic acid, to the terminal galactose of N-glycosylated proteins. Upregulation of ST6Gal1 is observed in many malignancies, and a large body of research has determined that ST6Gal1-medi...

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Detalles Bibliográficos
Autores principales: GC, Sajina, Bellis, Susan L., Hjelmeland, Anita B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465715/
https://www.ncbi.nlm.nih.gov/pubmed/36106023
http://dx.doi.org/10.3389/fmolb.2022.962908