Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination

BACKGROUND: This clinical trial evaluated a novel telomerase-targeting therapeutic cancer vaccine, UV1, in combination with ipilimumab, in patients with metastatic melanoma. Translational research was conducted on patient-derived blood and tissue samples with the goal of elucidating the effects of t...

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Detalles Bibliográficos
Autores principales: Ellingsen, Espen Basmo, Bounova, Gergana, Kerzeli, Iliana, Anzar, Irantzu, Simnica, Donjete, Aamdal, Elin, Guren, Tormod, Clancy, Trevor, Mezheyeuski, Artur, Inderberg, Else Marit, Mangsbo, Sara M., Binder, Mascha, Hovig, Eivind, Gaudernack, Gustav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465869/
https://www.ncbi.nlm.nih.gov/pubmed/36089578
http://dx.doi.org/10.1186/s12967-022-03624-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465869/
https://www.ncbi.nlm.nih.gov/pubmed/36089578
http://dx.doi.org/10.1186/s12967-022-03624-z

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