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Roles of microglia/macrophage and antibody in cell sheet transplantation in the central nervous system

BACKGROUND: We previously established a human mesenchymal stem cell (MSC) line that was modified to express trophic factors. Transplanting a cell sheet produced from this line in an amyotrophic lateral sclerosis mouse model showed a beneficial trend for mouse life spans. However, the sheet survived...

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Detalles Bibliográficos
Autores principales: Honda, Naoto, Watanabe, Yasuhiro, Tokuoka, Yuta, Hanajima, Ritsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465875/
https://www.ncbi.nlm.nih.gov/pubmed/36089602
http://dx.doi.org/10.1186/s13287-022-03168-5