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Roles of microglia/macrophage and antibody in cell sheet transplantation in the central nervous system
BACKGROUND: We previously established a human mesenchymal stem cell (MSC) line that was modified to express trophic factors. Transplanting a cell sheet produced from this line in an amyotrophic lateral sclerosis mouse model showed a beneficial trend for mouse life spans. However, the sheet survived...
Autores principales: | Honda, Naoto, Watanabe, Yasuhiro, Tokuoka, Yuta, Hanajima, Ritsuko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465875/ https://www.ncbi.nlm.nih.gov/pubmed/36089602 http://dx.doi.org/10.1186/s13287-022-03168-5 |
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