Mouse models of SMA show divergent patterns of neuronal vulnerability and resilience

BACKGROUND: Spinal muscular atrophy (SMA) is a form of motor neuron disease affecting primarily children characterised by the loss of lower motor neurons (MNs). Breakdown of the neuromuscular junctions (NMJs) is an early pathological event in SMA. However, not all motor neurons are equally vulnerabl...

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Detalles Bibliográficos
Autores principales: Woschitz, Victoria, Mei, Irene, Hedlund, Eva, Murray, Lyndsay M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465884/
https://www.ncbi.nlm.nih.gov/pubmed/36089582
http://dx.doi.org/10.1186/s13395-022-00305-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465884/
https://www.ncbi.nlm.nih.gov/pubmed/36089582
http://dx.doi.org/10.1186/s13395-022-00305-9

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