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Mouse models of SMA show divergent patterns of neuronal vulnerability and resilience
BACKGROUND: Spinal muscular atrophy (SMA) is a form of motor neuron disease affecting primarily children characterised by the loss of lower motor neurons (MNs). Breakdown of the neuromuscular junctions (NMJs) is an early pathological event in SMA. However, not all motor neurons are equally vulnerabl...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465884/ https://www.ncbi.nlm.nih.gov/pubmed/36089582 http://dx.doi.org/10.1186/s13395-022-00305-9 |