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Population pharmacokinetic study of pemetrexed in chinese primary advanced non-small cell lung carcinoma patients

The purposes of this study were to identify physiological and genetic factors that contributed to variability of pemetrexed (PEM) exposure and to optimize the dosing regimens for Chinese non-small cell lung carcinoma patients. A prospective population pharmacokinetics (PPK) research was performed in...

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Detalles Bibliográficos
Autores principales: Cao, Peng, Guo, Wei, Wang, Jun, Wu, Sanlan, Huang, Yifei, Wang, Yang, Liu, Yani, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466465/
https://www.ncbi.nlm.nih.gov/pubmed/36105185
http://dx.doi.org/10.3389/fphar.2022.954242