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Enaminone-based carboxylic acids as novel non-classical carbonic anhydrases inhibitors: design, synthesis and in vitro biological assessment

In searching for new molecular drug targets, Carbonic Anhydrases (CAs) have emerged as valuable targets in diverse diseases. CAs play critical functions in maintaining pH and CO(2) homeostasis, metabolic pathways, and much more. So, it is becoming attractive for medicinal chemists to design novel in...

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Detalles Bibliográficos
Autores principales: Abo-Ashour, Mahmoud F., Almahli, Hadia, Bonardia, Alessandro, Khalil, Amira, Al-Warhi, Tarfah, Al-Rashood, Sara T., Abdel-Aziz, Hatem A., Nocentini, Alessio, Supuran, Claudiu T., Eldehna, Wagdy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466612/
https://www.ncbi.nlm.nih.gov/pubmed/36000171
http://dx.doi.org/10.1080/14756366.2022.2114079