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Enaminone-based carboxylic acids as novel non-classical carbonic anhydrases inhibitors: design, synthesis and in vitro biological assessment
In searching for new molecular drug targets, Carbonic Anhydrases (CAs) have emerged as valuable targets in diverse diseases. CAs play critical functions in maintaining pH and CO(2) homeostasis, metabolic pathways, and much more. So, it is becoming attractive for medicinal chemists to design novel in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466612/ https://www.ncbi.nlm.nih.gov/pubmed/36000171 http://dx.doi.org/10.1080/14756366.2022.2114079 |