AKT and SGK kinases regulate cell migration by altering Scar/WAVE complex activation and Arp2/3 complex recruitment

Cell polarity and cell migration both depend on pseudopodia and lamellipodia formation. These are regulated by coordinated signaling acting through G-protein coupled receptors and kinases such as PKB/AKT and SGK, as well as the actin cytoskeletal machinery. Here we show that both Dictyostelium PKB a...

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Detalles Bibliográficos
Autores principales: Singh, Shashi Prakash, Paschke, Peggy, Tweedy, Luke, Insall, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466652/
https://www.ncbi.nlm.nih.gov/pubmed/36106016
http://dx.doi.org/10.3389/fmolb.2022.965921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466652/
https://www.ncbi.nlm.nih.gov/pubmed/36106016
http://dx.doi.org/10.3389/fmolb.2022.965921

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