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AKT and SGK kinases regulate cell migration by altering Scar/WAVE complex activation and Arp2/3 complex recruitment
Cell polarity and cell migration both depend on pseudopodia and lamellipodia formation. These are regulated by coordinated signaling acting through G-protein coupled receptors and kinases such as PKB/AKT and SGK, as well as the actin cytoskeletal machinery. Here we show that both Dictyostelium PKB a...
Autores principales: | Singh, Shashi Prakash, Paschke, Peggy, Tweedy, Luke, Insall, Robert H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466652/ https://www.ncbi.nlm.nih.gov/pubmed/36106016 http://dx.doi.org/10.3389/fmolb.2022.965921 |
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