P-Glycoprotein Aggravates Blood Brain Barrier Dysfunction in Experimental Ischemic Stroke by Inhibiting Endothelial Autophagy

P-glycoprotein (P-gp) is expressed on brain microvessel endothelial cells of blood-brain barrier (BBB) and elevated after cerebral ischemia. In this study, we explored the influence and potential mechanisms of P-gp on BBB function in experimental ischemic stroke in vivo and in vitro. Middle cerebral...

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Detalles Bibliográficos
Autores principales: Huang, Liangliang, Chen, Yan, Liu, Rui, Li, Binbin, Fei, Xuan, Li, Xiang, Liu, Ge, Li, Yunman, Xu, Baohui, Fang, Weirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2022
Materias:
Original Artcile
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466967/
https://www.ncbi.nlm.nih.gov/pubmed/36186136
http://dx.doi.org/10.14336/AD.2022.0225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466967/
https://www.ncbi.nlm.nih.gov/pubmed/36186136
http://dx.doi.org/10.14336/AD.2022.0225

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