Dietary Salt Disrupts Tricarboxylic Acid Cycle and Induces Tau Hyperphosphorylation and Synapse Dysfunction during Aging

Dietary salt causes synaptic deficits and tau hyperphosphorylation, which are detrimental to cognitive function. However, the specific effects of a high-salt diet on synapse and tau protein remain poorly understood. In this study, aged (15-month-old) C57BL/6 mice received a normal (0.5% NaCl) or hig...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Minghao, Wang, Yangyang, Wen, Jie, Jing, Feng, Zou, Qian, Pu, Yinshuang, Pan, Tingyu, Cai, Zhiyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466974/
https://www.ncbi.nlm.nih.gov/pubmed/36186135
http://dx.doi.org/10.14336/AD.2022.0220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466974/
https://www.ncbi.nlm.nih.gov/pubmed/36186135
http://dx.doi.org/10.14336/AD.2022.0220

Ejemplares similares