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Absence of TSC1 Accelerates CD8(+) T cell-mediated Acute Cardiac Allograft Rejection
Tuberous sclerosis complex (TSC) is an autosomal dominant disease caused by inactivating mutations in TSC1 or TSC2.Patients with TSC often require organ transplantation after organ failure. TSC1 serves as an important control node in immune cell development and responses; however, its effect on T ce...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JKL International LLC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466980/ https://www.ncbi.nlm.nih.gov/pubmed/36186130 http://dx.doi.org/10.14336/AD.2022.0224 |