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UPP1 Promotes Lung Adenocarcinoma Progression through Epigenetic Regulation of Glycolysis

Uridine phosphorylase 1 (UPP1) is a dimeric enzyme that plays an indispensable role in pyrimidine salvage as well as uridine homeostasis and is upregulated in various cancers, including LUAD. However, the function and underlying mechanisms of UPP1 in mediating LUAD cell progression are still largely...

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Detalles Bibliográficos
Autores principales: Wang, Xuan, Wang, Zheng, Huang, Renhong, Lu, Zhouyi, Chen, Xiaofeng, Huang, Dayu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466982/
https://www.ncbi.nlm.nih.gov/pubmed/36186123
http://dx.doi.org/10.14336/AD.2022.0218