Diminishing clinical impact for post-approval cancer clinical trials: A retrospective cohort study

BACKGROUND: Once a drug gets FDA approved, researchers often attempt to discover new applications in different indications. The clinical impact of such post-approval activities is uncertain. We aimed to compare the clinical impact of research efforts started after approval with those started before...

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Detalles Bibliográficos
Autores principales: Ouimet, Charlotte, Bouche, Gauthier, Kimmelman, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467301/
https://www.ncbi.nlm.nih.gov/pubmed/36094914
http://dx.doi.org/10.1371/journal.pone.0274115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467301/
https://www.ncbi.nlm.nih.gov/pubmed/36094914
http://dx.doi.org/10.1371/journal.pone.0274115

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