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Critical evaluation of an autologous peripheral blood mononuclear cell-based humanized cancer model

The use of humanized mouse models for oncology is rapidly expanding. Autologous patient-derived systems are particularly attractive as they can model the human cancer’s heterogeneity and immune microenvironment. In this study, we developed an autologous humanized mouse cancer model by engrafting NSG...

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Detalles Bibliográficos
Autores principales: Janakiraman, Harinarayanan, Becker, Scott A., Bradshaw, Alexandra, Rubinstein, Mark P., Camp, Ernest Ramsay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467357/
https://www.ncbi.nlm.nih.gov/pubmed/36095023
http://dx.doi.org/10.1371/journal.pone.0273076