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Critical evaluation of an autologous peripheral blood mononuclear cell-based humanized cancer model
The use of humanized mouse models for oncology is rapidly expanding. Autologous patient-derived systems are particularly attractive as they can model the human cancer’s heterogeneity and immune microenvironment. In this study, we developed an autologous humanized mouse cancer model by engrafting NSG...
Autores principales: | Janakiraman, Harinarayanan, Becker, Scott A., Bradshaw, Alexandra, Rubinstein, Mark P., Camp, Ernest Ramsay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467357/ https://www.ncbi.nlm.nih.gov/pubmed/36095023 http://dx.doi.org/10.1371/journal.pone.0273076 |
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