Effect of BBT-877, a novel inhibitor of ATX, on a mouse model of type 1 diabetic nephropathy

Diabetic nephropathy (DN) is one of the common microvascular complications of diabetes. Autotaxin (ATX) is an enzyme with lysophospholipase D activity, producing lysophosphatidic acid (LPA). LPA signaling has been implicated in renal fibrosis, thereby inducing renal dysfunction. BBT-877 is an orally...

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Detalles Bibliográficos
Autores principales: Lee, Jong Han, Khin, Phyu Phyu, Lee, GwangHee, Lim, Oh Kyung, Jun, Hee-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467391/
https://www.ncbi.nlm.nih.gov/pubmed/36036755
http://dx.doi.org/10.18632/aging.204249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467391/
https://www.ncbi.nlm.nih.gov/pubmed/36036755
http://dx.doi.org/10.18632/aging.204249

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