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Effect of BBT-877, a novel inhibitor of ATX, on a mouse model of type 1 diabetic nephropathy
Diabetic nephropathy (DN) is one of the common microvascular complications of diabetes. Autotaxin (ATX) is an enzyme with lysophospholipase D activity, producing lysophosphatidic acid (LPA). LPA signaling has been implicated in renal fibrosis, thereby inducing renal dysfunction. BBT-877 is an orally...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467391/ https://www.ncbi.nlm.nih.gov/pubmed/36036755 http://dx.doi.org/10.18632/aging.204249 |