Synergism of BCL-2 family inhibitors facilitates selective elimination of senescent cells

Accumulation of senescent cells in tissues with advancing age participates in the pathogenesis of several human age-associated diseases. Specific senescent secretome, the resistance of senescent cells to apoptotic stimuli, and lack of immune system response contribute to the accumulation of senescen...

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Detalles Bibliográficos
Autores principales: Rysanek, David, Vasicova, Pavla, Kolla, Jayaprakash Narayana, Sedlak, David, Andera, Ladislav, Bartek, Jiri, Hodny, Zdenek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467395/
https://www.ncbi.nlm.nih.gov/pubmed/35951353
http://dx.doi.org/10.18632/aging.204207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467395/
https://www.ncbi.nlm.nih.gov/pubmed/35951353
http://dx.doi.org/10.18632/aging.204207

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