Cargando…
Synergism of BCL-2 family inhibitors facilitates selective elimination of senescent cells
Accumulation of senescent cells in tissues with advancing age participates in the pathogenesis of several human age-associated diseases. Specific senescent secretome, the resistance of senescent cells to apoptotic stimuli, and lack of immune system response contribute to the accumulation of senescen...
Autores principales: | Rysanek, David, Vasicova, Pavla, Kolla, Jayaprakash Narayana, Sedlak, David, Andera, Ladislav, Bartek, Jiri, Hodny, Zdenek |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467395/ https://www.ncbi.nlm.nih.gov/pubmed/35951353 http://dx.doi.org/10.18632/aging.204207 |
Ejemplares similares
-
Dynamic PML protein nucleolar associations with persistent DNA damage lesions in response to nucleolar stress and senescence-inducing stimuli
por: Imrichova, Terezie, et al.
Publicado: (2019) -
Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence
por: Mrazkova, Blanka, et al.
Publicado: (2018) -
Selective elimination of senescent cells by mitochondrial targeting is regulated by ANT2
por: Hubackova, Sona, et al.
Publicado: (2018) -
DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase
por: Brazina, Jan, et al.
Publicado: (2015) -
Cytokines shape chemotherapy-induced and ‘bystander' senescence
por: Hodny, Zdenek, et al.
Publicado: (2010)