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Systemic lipolysis promotes physiological fitness in Drosophila melanogaster

Since interventions such as caloric restriction or fasting robustly promote lipid catabolism and improve aging-related phenotypical markers, we investigated the direct effect of increased lipid catabolism via overexpression of bmm (brummer, FBgn0036449), the major triglyceride hydrolase in Drosophil...

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Detalles Bibliográficos
Autores principales: Shang, Linshan, Aughey, Elizabeth, Kim, Huiseon, Heden, Timothy D., Wang, Lu, Najt, Charles P., Esch, Nicholas, Brunko, Sophia, Abrahante, Juan E., Macchietto, Marissa, Mashek, Mara T., Fairbanks, Todd, Promislow, Daniel E. L., Neufeld, Thomas P., Mashek, Douglas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467406/
https://www.ncbi.nlm.nih.gov/pubmed/36044277
http://dx.doi.org/10.18632/aging.204251