MicroRNA-148a induces apoptosis and prevents angiogenesis with bevacizumab in colon cancer through direct inhibition of ROCK1/c-Met via HIF-1α under hypoxia

Angiogenesis and antiapoptosis effects are the major factors influencing malignancy progression. Hypoxia induces multiple mechanisms involving microRNA (miRNA) activity. Vascular endothelial growth factor (VEGF) is correlated with angiogenesis. An antiapoptotic factor, myeloid leukemia 1 (Mcl-1) is...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsai, Hsiang-Lin, Tsai, Yueh-Chiao, Chen, Yen-Cheng, Huang, Ching-Wen, Chen, Po-Jung, Li, Ching-Chun, Su, Wei-Chih, Chang, Tsung-Kun, Yeh, Yung-Sung, Yin, Tzu-Chieh, Wang, Jaw-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467409/
https://www.ncbi.nlm.nih.gov/pubmed/35997665
http://dx.doi.org/10.18632/aging.204243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467409/
https://www.ncbi.nlm.nih.gov/pubmed/35997665
http://dx.doi.org/10.18632/aging.204243

Ejemplares similares