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Therapeutic Effects of Retinoic Acid in Lipopolysaccharide-Induced Cardiac Dysfunction: Network Pharmacology and Experimental Validation

PURPOSE: Sepsis, which is deemed as a systemic inflammation reaction syndrome in the face of infectious stimuli, is the primary cause of death in ICUs. Sepsis-induced cardiomyopathy (SIC) may derive from systemic inflammation reaction and oxidative stress. Retinoic acid (RA) is recognized by its ben...

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Detalles Bibliográficos
Autores principales: Wang, Xi, Kong, Chang, Liu, Pan, Zhou, Baofeng, Geng, Wujun, Tang, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467448/
https://www.ncbi.nlm.nih.gov/pubmed/36105385
http://dx.doi.org/10.2147/JIR.S358374