Cargando…

Therapeutic Effects of Retinoic Acid in Lipopolysaccharide-Induced Cardiac Dysfunction: Network Pharmacology and Experimental Validation

PURPOSE: Sepsis, which is deemed as a systemic inflammation reaction syndrome in the face of infectious stimuli, is the primary cause of death in ICUs. Sepsis-induced cardiomyopathy (SIC) may derive from systemic inflammation reaction and oxidative stress. Retinoic acid (RA) is recognized by its ben...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xi, Kong, Chang, Liu, Pan, Zhou, Baofeng, Geng, Wujun, Tang, Hongli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467448/ https://www.ncbi.nlm.nih.gov/pubmed/36105385 http://dx.doi.org/10.2147/JIR.S358374

Ejemplares similares

Identification of Potential Biomarkers for Ryanodine Receptor 1 (RYR1) Mutation-Associated Myopathies Using Bioinformatics Approach
por: Wang, Xi, et al.
Publicado: (2022)

Integrated Network Pharmacology and Experimental Validation Approach to Investigate the Therapeutic Effects of Capsaicin on Lipopolysaccharide-Induced Acute Lung Injury
por: Liu, Peihui, et al.
Publicado: (2022)

Progresses, Challenges, and Prospects of CRISPR/Cas9 Gene-Editing in Glioma Studies
por: Kang, Xianhui, et al.
Publicado: (2023)

Ferrostatin-1 alleviates lipopolysaccharide-induced cardiac dysfunction
por: Xiao, Zheng, et al.
Publicado: (2021)

Retinoic Acid Receptor Is a Novel Therapeutic Target for Postoperative Cognitive Dysfunction
por: Bao, Yongjie, et al.
Publicado: (2023)

Therapeutic effects of Panax notoginseng saponins in rheumatoid arthritis: network pharmacology and experimental validation
por: Ma, Xinnan, et al.
Publicado: (2023)

Therapeutic Targets of Bufalin on Renal Carcinoma and Mechanisms: Experimental Validation of Network Pharmacology Analysis
por: Zhang, Lei, et al.
Publicado: (2022)

Therapeutic Effects of Naringin in Rheumatoid Arthritis: Network Pharmacology and Experimental Validation
por: Aihaiti, Yirixiati, et al.
Publicado: (2021)

Therapeutic Effect of Costunolide in Autoimmune Hepatitis: Network Pharmacology and Experimental Validation
por: Huang, Zheng, et al.
Publicado: (2023)

Cardiac retinoic acid levels decline in heart failure
por: Yang, Ni, et al.
Publicado: (2021)

Dysbacteriosis-Derived Lipopolysaccharide Causes Embryonic Osteopenia through Retinoic-Acid-Regulated DLX5 Expression
por: You, Lingsen, et al.
Publicado: (2020)

IL-12p40 deletion aggravates lipopolysaccharide-induced cardiac dysfunction in mice
por: Liu, Menglin, et al.
Publicado: (2022)

Lipopolysaccharide induces mitochondrial dysfunction in rat cardiac microvascular endothelial cells
por: Vuda, M, et al.
Publicado: (2011)

Uncovering the mechanism of resveratrol in the treatment of diabetic kidney disease based on network pharmacology, molecular docking, and experimental validation
por: Chen, Shengnan, et al.
Publicado: (2023)

Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation
por: Shi, Lu, et al.
Publicado: (2022)

Synaptic Plasticity is Altered by Treatment with Pharmacological Levels of Retinoic Acid Acting Nongenomically However Endogenous Retinoic Acid has not been shown to have Nongenomic Activity
por: Duester, Gregg
Publicado: (2022)

Potential Therapeutic Effect of All-Trans Retinoic Acid on Atherosclerosis
por: Deng, Qile, et al.
Publicado: (2022)

Experimental effect of retinoic acids on apoptosis during the development of diabetic retinopathy
por: Nishikiori, Nami, et al.
Publicado: (2008)

Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis
por: Oehlers, Stefan H., et al.
Publicado: (2012)

Therapeutic effect of all-trans-retinoic acid (at-RA) on an autoimmune nephritis experimental model: role of the VLA-4 integrin
por: Escribese, María M, et al.
Publicado: (2007)

Cardiac laterality and ventricular looping in retinoic acid-treated rat embryos.
por: Kim, J. S., et al.
Publicado: (1999)

Ulinastatin attenuates lipopolysaccharide-induced cardiac dysfunction by inhibiting inflammation and regulating autophagy
por: Zhao, Pin, et al.
Publicado: (2020)

Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury
por: Kang, Xianhui, et al.
Publicado: (2019)

Research Progress on the Ability of Astragaloside IV to Protect the Brain Against Ischemia-Reperfusion Injury
por: Kang, Xianhui, et al.
Publicado: (2021)

Retinoic Acid Embryopathy
por: Mondal, Dipankar, et al.
Publicado: (2017)

COVID-19: Endogenous Retinoic Acid Theory and Retinoic Acid Depletion Syndrome
por: Sarohan, Aziz Rodan
Publicado: (2020)

Mechanisms of Quercetin against atrial fibrillation explored by network pharmacology combined with molecular docking and experimental validation
por: Tan, Xin, et al.
Publicado: (2022)

Divergent Roles for Airway Epithelial MMP7 and Retinoic Acid in Experimental Asthma
por: Goswami, Sangeeta, et al.
Publicado: (2009)

Functions for Retinoic Acid-Related Orphan Receptor Alpha (RORα) in the Activation of Macrophages During Lipopolysaccharide-Induced Septic Shock
por: Hams, Emily, et al.
Publicado: (2021)

Thymidine phosphorylase facilitates retinoic acid inducible gene-I induced endothelial dysfunction
por: Baris, Adrian, et al.
Publicado: (2023)

Reveals of quercetin’s therapeutic effects on oral lichen planus based on network pharmacology approach and experimental validation
por: Zhao, Zhibai, et al.
Publicado: (2022)

Therapeutic mechanism of baicalein in peritoneal dialysis-associated peritoneal fibrosis based on network pharmacology and experimental validation
por: Lu, Xiaohui, et al.
Publicado: (2023)

Network pharmacology analysis combined with experimental validation to explore the therapeutic mechanism of salidroside on intestine ischemia reperfusion
por: Chen, Feng, et al.
Publicado: (2023)

Pharmacological EZH2 inhibition combined with retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells
por: O’Brien, Eleanor, et al.
Publicado: (2023)

Pharmacological Mechanism of Shen Huang Chong Ji for Treating Alzheimer's Disease Based on Network Pharmacology and Experimental Validation
por: Tang, Lei, et al.
Publicado: (2022)

Integrated Network Pharmacology Analysis and Experimental Validation to Investigate the Molecular Mechanism of Triptolide in the Treatment of Membranous Nephropathy
por: Zhang, Ping Na, et al.
Publicado: (2022)

STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3
por: Li, Ning, et al.
Publicado: (2019)

Disruption of Retinoic Acid Receptor Alpha Reveals the Growth Promoter Face of Retinoic Acid
por: Somenzi, Giulia, et al.
Publicado: (2007)

Regulatory Role of Retinoic Acid in Male Pregnancy of the Seahorse
por: Li, Chunyan, et al.
Publicado: (2020)

Scutellaria baicalensis in the Treatment of Hepatocellular Carcinoma: Network Pharmacology Analysis and Experimental Validation
por: Cai, Xin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4obbt481n5ubl5qlfcu7kto25h