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DNA passes through cohesin’s hinge as well as its Smc3–kleisin interface

The ring model proposes that sister chromatid cohesion is mediated by co-entrapment of sister DNAs inside a single tripartite cohesin ring. The model explains how Scc1 cleavage triggers anaphase but has hitherto only been rigorously tested using small circular mini-chromosomes in yeast, where covale...

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Detalles Bibliográficos
Autores principales: Collier, James E, Nasmyth, Kim A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467508/
https://www.ncbi.nlm.nih.gov/pubmed/36094369
http://dx.doi.org/10.7554/eLife.80310