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Function and dynamics of the Mediator complex: novel insights and new frontiers
The Mediator complex was discovered in the early 1990s as a biochemically fractionated factor from yeast extracts that was necessary for activator-stimulated transcriptional activation to be observed in in vitro transcription assays. The structure of this large, multi-protein complex is now understo...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467533/ https://www.ncbi.nlm.nih.gov/pubmed/35708525 http://dx.doi.org/10.1080/21541264.2022.2085502 |