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Pseudolycorine chloride ameliorates Th17 cell-mediated central nervous system autoimmunity by restraining myeloid-derived suppressor cell expansion

CONTEXT: The alkaloids of Narcissus tazetta L. var. Chinensis Roem (Amaryllidaceae) have antitumor and antiviral activities. However, the immunopharmacological effects of one of its constituents, pseudolycorine chloride (PLY), have not been reported yet. OBJECTIVE: We evaluated the effect of PLY on...

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Detalles Bibliográficos
Autores principales: Zhang, Gan, Zhu, Xinying, Yang, Fan, Li, Juan, Leng, Xiao, Mo, Chunfen, Li, Limei, Wang, Yantang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467541/
https://www.ncbi.nlm.nih.gov/pubmed/36082828
http://dx.doi.org/10.1080/13880209.2022.2063344