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Loss of CD47 alters CD8+ T cell activation in vitro and immunodynamics in mice

CD47 has established roles in the immune system for regulating macrophage phagocytosis and lymphocyte activation, with growing evidence of its cell-intrinsic regulatory roles in natural killer and CD8+ T cells. CD47 limits antigen-dependent cytotoxic activities of human and murine CD8+ T cells, but...

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Detalles Bibliográficos
Autores principales: Nath, Pulak R., Pal-Nath, Dipasmita, Kaur, Sukhbir, Gangaplara, Arunkumar, Meyer, Thomas J., Cam, Margaret C, Roberts, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467551/
https://www.ncbi.nlm.nih.gov/pubmed/36105746
http://dx.doi.org/10.1080/2162402X.2022.2111909