Small ubiquitin-related modifier (SUMO)ylation of SIRT1 mediates (-)-epicatechin inhibited- differentiation of cardiac fibroblasts into myofibroblasts

CONTEXT: (-)-Epicatechin (EPI) is a crucial substance involved in the protective effects of flavanol-rich foods. Previous studies have indicated EPI has a cardioprotective effect, but the molecular mechanisms in inhibition of cardiac fibrosis are unclear. OBJECTIVE: We evaluated the effect of EPI in...

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Detalles Bibliográficos
Autores principales: Luo, Yingchun, Lu, Jing, Wang, Zeng, Wang, Lu, Wu, Guodong, Guo, Yuanyuan, Dong, Zengxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467557/
https://www.ncbi.nlm.nih.gov/pubmed/36086802
http://dx.doi.org/10.1080/13880209.2022.2101672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467557/
https://www.ncbi.nlm.nih.gov/pubmed/36086802
http://dx.doi.org/10.1080/13880209.2022.2101672

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