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The Influence of Lipid Matrix Composition on the Microenvironment of Levofloxacin in Liposomal Forms

We have studied the interaction of the antibacterial drug levofloxacin with lipid bilayers of various compositions: 100% DPPC and with the addition of 20% cardiolipin. For DPPC liposomes, levofloxacin was found to penetrate into the subpolar region at the lipid–water interface. The role of the anion...

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Detalles Bibliográficos
Autores principales: Le-Deygen, I. M., Safronova, A. S., Kolmogorov, I. M., Skuredina, A. A., Kudryashova, E. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467668/
https://www.ncbi.nlm.nih.gov/pubmed/36119964
http://dx.doi.org/10.1134/S1068162022040148