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Siglec-15 Regulates the Inflammatory Response and Polarization of Tumor-Associated Macrophages in Pancreatic Cancer by Inhibiting the cGAS-STING Signaling Pathway

Tumor-associated macrophages especially M2 phenotype macrophages play an important role in tumor progression and the formation of immunosuppressive tumor microenvironment. Previous studies indicated that infiltration of a large number of M2-macrophages was positively associated with a low survival r...

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Detalles Bibliográficos
Autores principales: Li, HuaGen, Zhu, RongXuan, Liu, XiaoLong, Zhao, Kai, Hong, DeFei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467737/
https://www.ncbi.nlm.nih.gov/pubmed/36105484
http://dx.doi.org/10.1155/2022/3341038