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Antibody stabilization for thermally accelerated deep immunostaining

Antibodies have diverse applications due to their high reaction specificities but are sensitive to denaturation when a higher working temperature is required. We have developed a simple, highly scalable and generalizable chemical approach for stabilizing off-the-shelf antibodies against thermal and...

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Detalles Bibliográficos
Autores principales: Lai, Hei Ming, Tang, Yumi, Lau, Zachary Y. H., Campbell, Robert A. A., Yau, Juno C. N., Chan, Caleb C. Y., Chan, Danny C. W., Wong, Tin Yan, Wong, Harriet K. T., Yan, Leo Y. C., Wu, William K. K., Wong, Sunny H., Kwok, Ka-Wai, Wing, Yun-Kwok, Lam, Henry H. N., Ng, Ho-Keung, Mrsic-Flogel, Thomas D., Mok, Vincent C. T., Chan, Jason Y. K., Ko, Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467915/
https://www.ncbi.nlm.nih.gov/pubmed/36050489
http://dx.doi.org/10.1038/s41592-022-01569-1