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[1,2,4] Triazolo [3,4-a]isoquinoline chalcone derivative exhibits anticancer activity via induction of oxidative stress, DNA damage, and apoptosis in Ehrlich solid carcinoma-bearing mice

Despite the advances made in cancer therapeutics, their adverse effects remain a major concern, putting safer therapeutic options in high demand. Since chalcones, a group of flavonoids and isoflavonoids, act as promising anticancer agents, we aimed to evaluate the in vivo anticancer activity of a sy...

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Detalles Bibliográficos
Autores principales: WalyEldeen, Amr Ahmed, El-Shorbagy, Haidan M., Hassaneen, Hamdi M., Abdelhamid, Ismail A., Sabet, Salwa, Ibrahim, Sherif Abdelaziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467967/
https://www.ncbi.nlm.nih.gov/pubmed/35881165
http://dx.doi.org/10.1007/s00210-022-02269-5