Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency

Functional oncogenic links between ErbB2 and ERRα in HER2+ breast cancer patients support a therapeutic benefit of co-targeted therapies. However, ErbB2 and ERRα also play key roles in heart physiology, and this approach could pose a potential liability to cardiovascular health. Herein, using integr...

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Detalles Bibliográficos
Autores principales: Dufour, Catherine R., Xia, Hui, B’chir, Wafa, Perry, Marie-Claude, Kuzmanov, Uros, Gainullina, Anastasiia, Dejgaard, Kurt, Scholtes, Charlotte, Ouellet, Carlo, Zuo, Dongmei, Sanguin-Gendreau, Virginie, Guluzian, Christina, Smith, Harvey W., Muller, William J., Audet-Walsh, Etienne, Sergushichev, Alexey A., Emili, Andrew, Giguère, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467976/
https://www.ncbi.nlm.nih.gov/pubmed/36097051
http://dx.doi.org/10.1038/s42003-022-03942-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467976/
https://www.ncbi.nlm.nih.gov/pubmed/36097051
http://dx.doi.org/10.1038/s42003-022-03942-4

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