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Ice thickness monitoring for cryo-EM grids by interferometry imaging
While recent technological developments contributed to breakthrough advances in single particle cryo-electron microscopy (cryo-EM), sample preparation remains a significant bottleneck for the structure determination of macromolecular complexes. A critical time factor is sample optimization that requ...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468024/ https://www.ncbi.nlm.nih.gov/pubmed/36097274 http://dx.doi.org/10.1038/s41598-022-16978-7 |