Improved immunoassay sensitivity and specificity using single-molecule colocalization

Enzyme-linked immunosorbent assays (ELISAs) are a cornerstone of modern molecular detection, but the technique still faces notable challenges. One of the biggest problems is discriminating true signal generated by target molecules versus non-specific background. Here, we developed a Single-Molecule...

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Detalles Bibliográficos
Autores principales: Hariri, Amani A., Newman, Sharon S., Tan, Steven, Mamerow, Dan, Adams, Alexandra M., Maganzini, Nicolò, Zhong, Brian L., Eisenstein, Michael, Dunn, Alexander R., Soh, H. Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468026/
https://www.ncbi.nlm.nih.gov/pubmed/36097164
http://dx.doi.org/10.1038/s41467-022-32796-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468026/
https://www.ncbi.nlm.nih.gov/pubmed/36097164
http://dx.doi.org/10.1038/s41467-022-32796-x

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