E2F1/CKS2/PTEN signaling axis regulates malignant phenotypes in pediatric retinoblastoma

Retinoblastoma (RB) is the most common pediatric intraocular malignancy and is a serious vision- and life-threatening disease. The biallelic mutation of the retinoblastoma gene RB1 is the initial event in the malignant transformation of RB, but the exact molecular mechanism is still unclear. E2F tra...

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Detalles Bibliográficos
Autores principales: Chen, Meng, Zhao, Zhaozhao, Wu, Lianqun, Huang, Jiancheng, Yu, Peng, Qian, Jiang, Ni, Ting, Zhao, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468144/
https://www.ncbi.nlm.nih.gov/pubmed/36096885
http://dx.doi.org/10.1038/s41419-022-05222-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468144/
https://www.ncbi.nlm.nih.gov/pubmed/36096885
http://dx.doi.org/10.1038/s41419-022-05222-9

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