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E2F1/CKS2/PTEN signaling axis regulates malignant phenotypes in pediatric retinoblastoma
Retinoblastoma (RB) is the most common pediatric intraocular malignancy and is a serious vision- and life-threatening disease. The biallelic mutation of the retinoblastoma gene RB1 is the initial event in the malignant transformation of RB, but the exact molecular mechanism is still unclear. E2F tra...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468144/ https://www.ncbi.nlm.nih.gov/pubmed/36096885 http://dx.doi.org/10.1038/s41419-022-05222-9 |