Cargando…

Reactivating hippocampal-mediated memories during reconsolidation to disrupt fear

Memories are stored in the brain as cellular ensembles activated during learning and reactivated during retrieval. Using the Tet-tag system in mice, we label dorsal dentate gyrus neurons activated by positive, neutral or negative experiences with channelrhodopsin-2. Following fear-conditioning, thes...

Descripción completa

Detalles Bibliográficos
Autores principales: Grella, Stephanie L., Fortin, Amanda H., Ruesch, Evan, Bladon, John H., Reynolds, Leanna F., Gross, Abby, Shpokayte, Monika, Cincotta, Christine, Zaki, Yosif, Ramirez, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468169/
https://www.ncbi.nlm.nih.gov/pubmed/36096993
http://dx.doi.org/10.1038/s41467-022-32246-8