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Reactivating hippocampal-mediated memories during reconsolidation to disrupt fear
Memories are stored in the brain as cellular ensembles activated during learning and reactivated during retrieval. Using the Tet-tag system in mice, we label dorsal dentate gyrus neurons activated by positive, neutral or negative experiences with channelrhodopsin-2. Following fear-conditioning, thes...
Autores principales: | Grella, Stephanie L., Fortin, Amanda H., Ruesch, Evan, Bladon, John H., Reynolds, Leanna F., Gross, Abby, Shpokayte, Monika, Cincotta, Christine, Zaki, Yosif, Ramirez, Steve |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468169/ https://www.ncbi.nlm.nih.gov/pubmed/36096993 http://dx.doi.org/10.1038/s41467-022-32246-8 |
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