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Lactate-induced lactylation in skeletal muscle is associated with insulin resistance in humans
Elevated circulating lactate has been associated with obesity and insulin resistance. The aim of the current study was to determine if lactate-induced lysine lactylation (kla), a post-translational modification, was present in human skeletal muscle and related to insulin resistance. Fifteen lean (Bo...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468271/ https://www.ncbi.nlm.nih.gov/pubmed/36111162 http://dx.doi.org/10.3389/fphys.2022.951390 |