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Lactate-induced lactylation in skeletal muscle is associated with insulin resistance in humans

Elevated circulating lactate has been associated with obesity and insulin resistance. The aim of the current study was to determine if lactate-induced lysine lactylation (kla), a post-translational modification, was present in human skeletal muscle and related to insulin resistance. Fifteen lean (Bo...

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Detalles Bibliográficos
Autores principales:	Maschari, Dominic, Saxena, Gunjan, Law, Timothy D., Walsh, Erin, Campbell, Mason C., Consitt, Leslie A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468271/ https://www.ncbi.nlm.nih.gov/pubmed/36111162 http://dx.doi.org/10.3389/fphys.2022.951390

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