The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3

Choanoflagellates are primitive protozoa used as models for animal evolution. They express a large variety of multi-domain proteins contributing to adhesion and cell communication, thereby providing a rich repertoire of molecules for biotechnology. Adhesion often involves proteins adopting a β-trefo...

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Detalles Bibliográficos
Autores principales: Notova, Simona, Bonnardel , François, Rosato, Francesca, Siukstaite, Lina, Schwaiger, Jessica, Lim, Jia Hui, Bovin, Nicolai, Varrot, Annabelle, Ogawa, Yu, Römer, Winfried, Lisacek, Frédérique, Imberty, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468336/
https://www.ncbi.nlm.nih.gov/pubmed/36097056
http://dx.doi.org/10.1038/s42003-022-03869-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468336/
https://www.ncbi.nlm.nih.gov/pubmed/36097056
http://dx.doi.org/10.1038/s42003-022-03869-w

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