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Concentration-dependent thermodynamic analysis of the partition process of small ligands into proteins
In the category of functional low-affinity interactions, small ligands may interact with multiple protein sites in a highly degenerate manner. Better conceived as a partition phenomenon at the molecular interface of proteins, such low-affinity interactions appear to be hidden to our current experime...
Autores principales: | Cirqueira, Leonardo, Stock, Letícia, Treptow, Werner |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468351/ https://www.ncbi.nlm.nih.gov/pubmed/36147679 http://dx.doi.org/10.1016/j.csbj.2022.08.049 |
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