Inflammation aggravated the hepatotoxicity of triptolide by oxidative stress, lipid metabolism disorder, autophagy, and apoptosis in zebrafish

Triptolide is a major compound isolated from the Tripterygium wilfordii Hook that is mainly used for the treatment of autoimmune disorders and inflammatory diseases. Though triptolide-induced hepatotoxicity has been widely reported, the hepatic effects when the patients are in an inflammatory state...

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Detalles Bibliográficos
Autores principales: Li, Chenqinyao, Zhang, Changqing, Zhu, Chengyue, Zhang, Jie, Xia, Qing, Liu, Kechun, Zhang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468416/
https://www.ncbi.nlm.nih.gov/pubmed/36110530
http://dx.doi.org/10.3389/fphar.2022.949312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468416/
https://www.ncbi.nlm.nih.gov/pubmed/36110530
http://dx.doi.org/10.3389/fphar.2022.949312

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