Ultra-Rare BRD9 Loss-of-Function Variants Limit the Antiviral Action of Interferon

The human type I interferon (IFN) system is central to innate immune defense, and is essential to protect individuals against severe viral disease. Consequently, genetic disruption of IFN signaling or effector mechanisms is extremely rare, as affected individuals typically suffer life-threatening in...

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Detalles Bibliográficos
Autores principales: Mair, Nina K., Hale, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468519/
https://www.ncbi.nlm.nih.gov/pubmed/36100643
http://dx.doi.org/10.1038/s41598-022-19648-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468519/
https://www.ncbi.nlm.nih.gov/pubmed/36100643
http://dx.doi.org/10.1038/s41598-022-19648-w

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