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Ultra-Rare BRD9 Loss-of-Function Variants Limit the Antiviral Action of Interferon
The human type I interferon (IFN) system is central to innate immune defense, and is essential to protect individuals against severe viral disease. Consequently, genetic disruption of IFN signaling or effector mechanisms is extremely rare, as affected individuals typically suffer life-threatening in...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468519/ https://www.ncbi.nlm.nih.gov/pubmed/36100643 http://dx.doi.org/10.1038/s41598-022-19648-w |