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Highly Efficient DNA Reporter for CRISPR/Cas12a-Based Specific and Sensitive Biosensor
In addition to cis-cleavage activity that recognizes and cleaves nucleic acid sequences, a trans-cleavage activity that indiscriminately and non-specifically cleaves single-stranded DNA or RNA has been discovered in some Cas proteins, including Cas12a and Cas13a. Various detection methods using this...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean BioChip Society (KBCS)
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468524/ https://www.ncbi.nlm.nih.gov/pubmed/36117747 http://dx.doi.org/10.1007/s13206-022-00081-0 |