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Highly Efficient DNA Reporter for CRISPR/Cas12a-Based Specific and Sensitive Biosensor

In addition to cis-cleavage activity that recognizes and cleaves nucleic acid sequences, a trans-cleavage activity that indiscriminately and non-specifically cleaves single-stranded DNA or RNA has been discovered in some Cas proteins, including Cas12a and Cas13a. Various detection methods using this...

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Detalles Bibliográficos
Autores principales: Lee, Seungjin, Nam, Deahan, Park, Jung Soo, Kim, Seokjoon, Lee, Eun Sung, Cha, Byung Seok, Park, Ki Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean BioChip Society (KBCS) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468524/
https://www.ncbi.nlm.nih.gov/pubmed/36117747
http://dx.doi.org/10.1007/s13206-022-00081-0