One-pot synthesis, molecular docking, ADMET, and DFT studies of novel pyrazolines as promising SARS-CoV-2 main protease inhibitors

Pyrazoline and its derivatives have numerous prominent pharmacological effects. Focusing on its anti-viral property, we have designed and synthesized three novel pyrazoline derivatives (A1–A3) through one-pot three components and characterized them using different spectroscopic techniques (FT-IR, (1...

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Detalles Bibliográficos
Autores principales: Salih, Rezan Huseen Hama, Hasan, Aso Hameed, Hussein, Awaz Jamil, Samad, Mohammed Kareem, Shakya, Sonam, Jamalis, Joazaizulfazli, Hawaiz, Farouq Emam, Pratama, Mohammad Rizki Fadhil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468527/
http://dx.doi.org/10.1007/s11164-022-04831-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468527/
http://dx.doi.org/10.1007/s11164-022-04831-5

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